Woman drinking large glass of milk



When it comes to chemicals and nutrients, your body is very particular. It functions best when everything is balanced and in the right quantities. When your hormones are slightly out of whack, you see the signs right away. The same is true when you have too much or too little of essential nutrients: Your body responds unfavorably. A clear example of this can be seen in two calcium disorders: hypercalcemia (too much) and hypocalcemia (too little). In this blog, our experienced team of specialists at Palmetto Endocrinology explain the causes and symptoms of, and treatments for, hypocalcemia.


Why your body needs calcium

The mineral calcium serves several functions in your body’s day-to-day operation. Your muscles rely on calcium for their ability to move, your nerves count on calcium to relay messages to your brain, and your bones need calcium to regenerate and stay strong.

When your calcium supply falls — hypocalcemia — you start to see the signs, including:

If you ignore your hypocalcemia and it advances, you may have seizures, arrhythmias, voice box spasms, or heart failure.


What causes hypocalcemia?

There are many factors that can lead to hypocalcemia, but they generally fall into one of two categories: you’re not consuming enough calcium, or something is interfering with your ability to absorb calcium. Here are some of the specific culprits that cause hypocalcemia:



Your parathyroid glands secrete hormones that regulate the calcium and phosphorus in your body. If your parathyroid is malfunctioning and you have low levels of parathyroid hormones (hypoparathyroidism), you end up with hypocalcemia.

Hypoparathyroidism can result from an autoimmune disease, genetic makeup, neck surgery, insufficient intake of magnesium, or radiation during cancer treatment.


Poor diet

Your body doesn’t produce its own calcium, so it relies on adequate consumption of calcium, which can be found in foods such as dairy products, seeds, beans, lentils, almonds, leafy greens, and edamame, to name a few.

But your body can’t process calcium on its own; it needs vitamin D to facilitate absorption. You can get vitamin D by eating salmon, orange juice, and fortified cereals — and by spending some time in the sun.



Infections, kidney disease, and some intestinal disorders can mess with your ability to maintain proper calcium levels. Babies can suffer from hypocalcemia if the mother has diabetes and progressing cancer can deplete your calcium levels as well.



Certain anti-epileptic medications are known to rob patients of calcium, including phenytoin (Dylantin), rifampin, and phenobarbital.


Stress and anxiety

Under extreme stress, especially conditions that include hyperventilating, your body may respond with respiratory alkalosis, which in turn leads to hypocalcemia.


Are you at risk for hypocalcemia?

Anyone with a history of gastrointestinal disorders, liver or kidney failure, pancreatitis, or anxiety may be at risk for hypocalcemia. Fortunately, our team is highly experienced in diagnosing and treating hypocalcemia.

Although we treat your symptoms promptly to help you get back to normal, we’re most concerned with the underlying cause of your condition. Once we determine the reason behind the problem, we can treat the source, so you have a chance of eliminating the condition.

Your treatment may be as simple as a few lifestyle changes and dietary supplements, or you may require treatment to address a damaged kidney or liver. Once you meet with our team at Palmetto Endocrinology, we can get to the bottom of your hypocalcemia and let you know which treatment plan is best for you.

Joseph W. Mathews, MD, FACP, FACE, ECNU, CCD Joseph Mathews, MD, FACP, FACE, ECNU, CCD Joseph W. Mathews M.D., a board certified Endocrinologist and Medical Director of Palmetto Endocrinology, was born and raised in South Carolina. He earned his Bachelor of Science in Biology from the College of Charleston, Cum Laude. He then achieved his M.D. at the Medical University of South Carolina where he also completed his residency in Internal Medicine and a Fellowship in Endocrinology, Diabetes, and Metabolism. Dr. Mathews is also a Fellow of both the American College of Endocrinology and the American College of Physicians, holds an Endocrine Certification in Neck Ultrasound (ECNU) and is a Certified Clinical Densitometrist (CCD). He has extensive experience performing ultrasound guided fine needle aspiration biopsies. His practice includes a range of specializations including prescribing and fitting patients with insulin pumps. Dr. Mathews' practice has drawn patients from out of state to benefit from his expertise in thyroid disorders, diabetes, cortisol problems and their Endocrine disorders.

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